ThyroVantage HT™

ThyroVantage HT™

Thyroid Support

90 Vegetarian Capsules ( SKU: 9671, NPN: 80057582 )

Benefits

  • Z guggulsterone from Commiphora mukul stimulates thyroid function in vivo7
  • Withania somnifera promotes T4 function in vivo8
  • Added pantothenic acid to help support adrenal gland responsiveness9
  • In vivo manganese supports the creation of triiodothyronine (T3)10
  • Copper is linked to decreased plasma T3 concentrations in animals and humans11
  • Suitable for vegetarians

Feature Summary

Subclinical hypothyroidism (SHT) has been reported to present in 4 to 20% of the adult population.1 Patients with this thyroid disorder typically present with a serum TSH that can range from 5 to 9 mU/L along with varying degrees of symptomatology including bradycardia, constipation, dry skin, hoarseness, fatigue and muscle cramps.2,3 In addition, untreated SHT may have significant health consequences as it increases the risk for coronary heart disease (dyslipidemia, endothelial vascular dysfunction) in adults.4 While there are a number of prescriptive treatment options including low doses of L-thyroxine or whole gland thyroid, both nutritional and herbal remedies are useful therapeutic adjuncts. The amino acid L-tyrosine, as found in ThyroVantage HT, is an important nutritional precursor for thyroxine (T4). Biochemically, L-tyrosine is iodinated from thyroglobulin to form 3,5 diiodotyrosine which in turn is oxidized to the hormone thyroxine (T4).5 Iodide is another important factor in thyroid function with the oral administration of 500 mcg per day resulting in a significant increase in TRH-stimulated serum TSH concentrations.6

Medicinal Ingredients

Serving Size: 1 Vegetarian Capsule
Servings per Container: 90

Each Capsule Contains:
L-Tyrosine ............................................................................................................250 mg
Ashwagandha Extract (Withania somnifera) (root) (1.5% Withanolides) ..............75 mg
Guggul Extract (Commiphora mukul) (gum oleoresin) (2.5% Guggulsterone).......60 mg
d-Pantothenic Acid (Calcium d-Pantothenate).......................................................50 mg
Copper (Cupric Gluconate)..................................................................................250 mcg
Manganese (Citrate)............................................................................................250 mcg
Iodine (Potassium Iodide) .....................................................................................50 mcg
Selenium (Selenomethionine)...............................................................................25 mcg

Non-Medicinal Ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), microcrystalline cellulose, vegetable grade magnesium stearate (lubricant).

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

For adult use only. Consult a health care practitioner prior to use if you are following a low protein diet. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. Do not use if you are pregnant or breastfeeding. Keep out of reach of children.

Drug Interactions

Do not take with warfarin.12

  1. Biondi B. Natural history, diagnosis and management of subclinical thyroid function. Best Pract Res Clin Endo Metab. 2012;26:431-446.
  2. Khandelwal D, Tandon N. Overt and subclinical hypothyroidism: who to treat and how. Drugs, 2012;72:17-33.
  3. Adlin V. Subclinical Hypothyroidism: Deciding When to Treat. Am Fam Physician.1998;57:776-780.
  4. Cooper DS. Subclinical thyroid disease. Lancet, 2012;379:1142-54.
  5. Ramakrishnan S. Textbook of Medical Biochemistry 3rd ed. London, Orient Longman, 2004.
  6. Gardner DF, Centor RM, Utiger RD. Effects of low dose iodide supplementation on thyroid function in normal men. Clin Endocrinol. 1988;28:283-288.
  7. Tripathi YB, Malhotra OP, Tripathi SN. Thyroid Stimulating Action of Z-Guggulsterone Obtained from Commiphora mukul. Planta Med. 1984;50:78-80.
  8. Panda S, Kar A. Withania somnifera and Bauhinia purpurea in the regulation of circulating thyroid hormone concentration in female mice. J Ethnopharmacol. 1999;67:233-39.
  9. Jaroenporn S, Yamamoto T, Itabashi A, Nakamura K, Azumano I, Watanabe G, Taya K. Effects of pantothenic acid supplementation on adrenal steroid secretion from male rats. Biol Pharm Bull. 2008;31:505-8.
  10. Eder K, Kralik A, Kirchgessner M. The effect of manganese supply on thyroid hormone metabolism in the offspring of manganese-depleted dams. Biol Trace Elem Res.1996;55:137-45.
  11. Arthur JR, Beckett GJ. Thyroid function. Br Med Bull. 1999;55:658-68.
  12. Al Faraj S. Antagonism of the anticoagulant effect of warfarin caused by the use of Commiphora molmol as a herbal medication: a case report. Ann Trop Med Parasitol. 2005;99:219-20.