BioFoundation-G™

BioFoundation-G™

Multiple Vitamin & Mineral Formula

180 Tablets ( SKU: 9476, NPN: 80051438 )

Benefits

  • A full spectrum of vitamins and minerals
  • Provides rate-limiting nutrients for glutathione production, necessary for xenobiotic detoxification
  • Contains clinical doses of resveratrol, lipoic acid, CoQ10, milk thistle, and green tea extract
  • Broad-spectrum antioxidant support, including bilberry and citrus extracts, lipoic acid, lycopene, and lutein
  • Highly bioactive and bioavailable nutrients, such as pyridoxal-5-phosphate and vitamin K2 (Menaquinone 7)

Feature Summary

BioFoundation-G is a comprehensive vitamin and mineral supplement to support healthy living in the modern world. A broad-spectrum and highly bioavailable multivitamin and mineral, BioFoundation-G’s formulation uses clinically driven research to provide the nutritional foundation needed for the modern environment. This complete multivitamin and mineral formula contains clinical doses of nutrients such as N-acetyl-cysteine and R-alpha-lipoic acid, well established to increase cellular levels of glutathione, the most prevalent intercellular antioxidant.1,2,3 Glutathione is one of the most important conjugators of numerous environmental and endogenous toxins. It is known to be depleted not only by xenobiotics, but also by chronic conditions such as inflammatory and neurodegenerative diseases.4,5,6,7,8

Glutathione support is linked to lower rates of cell death and apoptosis.9 BioFoundation-G provides physiologically relevant doses of hepatoprotectors such as milk thistle, antioxidants, mitochondrial bioenergetic enhancers such as CoQ10, and co-factors for critical detoxification enzymes.10,11 It also provides the biological modifiers natural trans-resveratrol and green tea phytosome, two nutrients shown to have anti-inflammatory, weight management, anti-aging, cardiovascular, and stress-related benefits.12,13,14,15

Medicinal Ingredients

Serving Size: 1 Tablet
Servings per Container: 180

Each Tablet:
Vitamin A (Palmitate)............................................................................ 500 IU (150 mcg RAE)
Vitamin B1 (Thiamine Hydrochloride)..................................................4.2 mg
Vitamin B2 (Riboflavin)...................................................................4.2 mg
Vitamin B3 (Niacin)....................................................................... 12.5 mg
Vitamin B3 (Niacinamide) ............................................................ 33.3 mg
Vitamin B5 (Pantothenic Acid).......................................................16.7 mg
Vitamin B6 (Pyridoxine Hydrochloride/Pyridoxal 5-Phosphate).....2.5 mg
Biotin..............................................................................................8.3 mcg
Betaine Hydrochloride................................................................. 16.7 mg
Folic Acid (Folate)............................................................................83 mcg
Vitamin B12 (Methylcobalamin).....................................................167 mcg
Para-Aminobenzoic Acid (PABA) ...................................................4.2 mg
Choline (Bitartrate)..........................................................................4.2 mg
Inositol ............................................................................................4.2 mg
Vitamin C (Ascorbic Acid)...............................................................167 mg
Vitamin D3 (Cholecalciferol)...........................................................333 IU (8.3 mcg)
Vitamin E (d-Gamma-Tocopherol).................................................33.3 mg
Vitamin K2 (Menaquinone) (MK-7) (Natto Bean) ...........................7.5 mcg
Boron (Citrate)...............................................................................41.7 mcg
Calcium (HVP* Chelate)............................................................... 16.7 mg
Chromium (Polynicotinate).............................................................33.3 mcg
Copper (HVP* Chelate)................................................................. 170 mcg
Iodine (Ascophyllum nodosum) (whole plant).................................. 50 mcg
Magnesium (HVP* Chelate).......................................................... 33.3 mg
Manganese (Citrate).........................................................................0.8 mg
Molybdenum (Citrate).....................................................................66.7 mcg
Potassium (Citrate)...........................................................................6.8 mg
Selenium (Selenomethionine)........................................................33.3 mcg
Vanadium (Citrate)...........................................................................2.5 mcg
Zinc (Citrate)....................................................................................2.5 mg
Bilberry Extract (Vaccinium myrtillus) (fruit) (36% Anthocyanosides).......6.6 mg
Citrus Bioflavonoids 4:1 Extract (Citrus limon, Citrus sinensis, Citrus paradisi) (fruit).......8.3 mg
Coenzyme Q10 (Microorganism).....................................................8.3 mg
Green Tea Phytosome® (Camellia sinensis, Glycine max) (leaf, seed) (13% EGCG**).......8.3 mg
Hesperidin (Citrus sinensis) (fruit)...................................................4.2 mg
Lutein (Tagetes erecta) (herb flowering oleoresin).........................550 mcg
Lycopene (Lycopersicon esculentum) (fruit)....................................280 mcg
Silybin Phytosome® (Silybum marianum, Glycine max) (fruit, seed) (15% Silybin).........25 mg
N-acetyl-L-cysteine............................................................................25 mg
R-alpha-Lipoic Acid........................................................................ 41.7 mg
ResveratrolRich® Proprietary Blend
[Wine Grape (Vitis vinifera) (fruit), Purified Japanese Knotweed (Polygonum cuspidatum) (root)]...............................................................................................33.3 mg
Providing Natural Trans-Resveratrol.............................................. 16.7 mg
*HVP: Hydrolyzed Vegetable Protein
**EGCG: epigallocatechin-3-gallate

Non-Medicinal Ingredients

Microcrystalline cellulose, croscarmellose sodium, coating (carbohydrate gum [cellulose], glycerin), vegetable grade magnesium stearate (lubricant).

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, egg, fish, shellfish, salt, tree nuts, or GMOs. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

Consult a health care practitioner if you are taking blood thinners, or if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you have diabetes or kidney stones, or if you are taking sulfonamides or blood pressure medication. Consult a health care practitioner prior to use if you are taking prescription medication, as resveratrol may alter the effectiveness of these medications. Hypersensitivity (e.g., allergy) has been known to occur, in which case discontinue use. Do not use this product if you are taking antibiotics or nitroglycerin. Keep out of reach of children.

Drug Interactions

Vitamin K supplementation may decrease the efficacy of warfarin, or require more close monitoring of its administration.16 This product contains nutrients known to reduce hypertension and hyperglycemia, and may require lower dosing or discontinuation of related medications.14,16

  1. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., et al. (2007). N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency. Current opinion in pharmacology, 7(4), 355–359.
  2. Shay, K. P., Moreau, R. F., Smith, E. J., et al. (2009). Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et biophysica acta, 1790(10), 1149–1160.
  3. Becker, K., Pons-Kühnemann, J., Fechner, A., et al. (2005). Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor – a pilot study. Redox Report, 10(4), 215–226.
  4. Awasthi, Y. C., Chaudhary, P., Vatsyayan, R., et al. (2009). Physiological and pharmacological significance of glutathione-conjugate transport. Journal of toxicology and environmental health. Part B, Critical reviews, 12(7), 540–551.
  5. Ludewig, G., Srinivasan, A., &Robertson, L. W. (2000). Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion. Central European journal of public health, 8 Suppl, 15–17.
  6. Ahmed, T., Tripathi, A. K., Ahmed, R. S., et al. (2008). Endosulfan-induced apoptosis and glutathione depletion in human peripheral blood mononuclear cells: Attenuation by N-acetylcysteine. Journal of biochemical and molecular toxicology, 22(5), 299–304.
  7. Lee, D. H., &Jacobs, D. R., Jr (2009). Serum gamma-glutamyltransferase: new insights about an old enzyme. Journal of epidemiology and community health, 63(11), 884–886.
  8. Ljubisavljevic, S., Stojanovic, I., Cvetkovic, T., et al. (2014). Glutathione homeostasis disruption of erythrocytes, but not glutathione peroxidase activity change, is closely accompanied with neurological and radiological scoring of acute CNS inflammation. Neuroimmunomodulation, 21(1), 13–20.
  9. Circu, M. L., &Aw, T. Y. (2012). Glutathione and modulation of cell apoptosis. Biochimica et biophysica acta, 1823(10), 1767–1777.
  10. Rosenfeldt, F., Marasco, S., Lyon, W., et al. (2005). Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue. The Journal of thoracic and cardiovascular surgery, 129(1), 25–32.
  11. Kiruthiga, P. V., Shafreen, R. B., Pandian, S. K., et al. (2007). Silymarin protection against major reactive oxygen species released by environmental toxins: exogenous H2O2 exposure in erythrocytes. Basic &clinical pharmacology &toxicology, 100(6), 414–419.
  12. Wightman, E. L., Haskell-Ramsay, C., Reay, J. L., et al. (2015). The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. The British Journal of Nutrition, 114(9), 1427­–1437.
  13. Hoseini, A., Namazi, G., Farrokhian, A., et al. (2019). The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. Food &function, 10(9), 6042–6051.
  14. Brasnyó, P., Molnár, G. A., Mohás, M., et al. (2011). Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. The British journal of nutrition, 106(3), 383–389
  15. Gilardini, L., Pasqualinotto, L., Di Pierro, F., et al. (2016). Effects of Greenselect Phytosome® on weight maintenance after weight loss in obese women: a randomized placebo-controlled study. BMC complementary and alternative medicine, 16, 233.
  16. Ford, S. K., Misita, C. P., Shilliday, B. B., et al. (2007). Prospective study of supplemental vitamin K therapy in patients on oral anticoagulants with unstable international normalized ratios. Journal of thrombosis and thrombolysis, 24(1), 23–27.