Ubiquinol CoQ10

Ubiquinol CoQ10

Bioactive and Reduced Form · 200 mg

200 mg

60 Softgels ( SKU: 9707U )

Benefits

  • Offers a highly absorbable and bioavailable form of CoQ10
  • Increases plasma levels of CoQ10 significantly more per mg compared to ubiquinone
  • Allows for higher peak plasma levels of CoQ10, especially when higher plasma CoQ10 are required
  • Kaneka Q+ brand for ubiquinol is naturally produced via yeast fermentation, and is free of the impurities of synthetically-processed CoQ10
  • A base of organic flaxseed oil improves solubility 
  • GMO free, allergen free, and Kosher certified

Feature Summary

CoQ10 is commonly called ubiquinone because it is ubiquitous throughout the body and found in nearly every cell. The active form of the molecule, ubiquinol, is a fat-soluble antioxidant that supports healthy fats such as those that make up cellular and mitochondrial membranes, as well as both HDL and LDL cholesterol.* However, CoQ10’s most important role is in cellular respiration, the process of generating the energy (ATP) that all cells need for optimal health.*1,2,3

Because its role in energy production is so critical, it is particularly important in cells with high-energy demands, such as the heart. This helps explain why CoQ10 has shown such significant cardiovascular support for maintaining normal blood pressure already within the normal range and supporting myocardial health.* High levels of oxidative stress often have correspondingly low levels of CoQ10.*4,5,6,7,8,9,10  CoQ10 is a source of antioxidant activity.* Moderate amounts, ranging from 300–600 mg per day, have been used to increase the effects of CoQ10, help support normal fertility by maintaining ovarian and testicular health, and help maintain cardiovascular health.*11,12

Kaneka Q+ ubiquinol provides the form of CoQ10 found in 95% of human tissues. Higher levels of ubiquinol compared to ubiquinone are a sign of better cellular support.*13 Kaneka Q+ ubiquinol has also been shown to be more soluble than ubiquinone, more effectively increasing blood levels of this nutrient so critical to energy production.*14,15,16 A base of organic flaxseed oil improves the solubility of ubiquinol and has heart-healthy omega-3 fatty acids. Flaxseed oil has alpha-linolenic acid, an oil associated with cardiovascular support.*17

Supplement Facts:

Allergens:

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs.

Dosage:

Suggested Usage: 1 softgel per day or as directed by a health care professional.

Contraindications

No significant contraindications.

Drug Interactions

Although existing evidence has not found an interaction, CoQ10 resembles vitamin K structurally, potentially interfering with the anticoagulant warfarin. Close monitoring of the INR is recommended with CoQ10 introduction in these patients.18

  1. Potgieter, M., Pretorius, E., Pepper, M.S., et al. (2013). Nutrition Review, 71(3), 180-188.
  2. Littarru, G.P., & Tiano, L. (2010). Nutrition, 26(3), 250-254.
  3. Littarru, G.P., & Tiano, L. (2007). Molecular Biotechnology, 37(1), 31-37.
  4. Molyneux, S.L., Florkowski, C.M., George, P.M., et al. (2008). Journal of the American College of Cardiology, 52(18), 1435-1441.
  5. Lei, L., & Liu, Y. (2017). BMC Cardiovascular Disorders, 17(1), 196.
  6. Pringshelm, T., Davenport, W., Mackie, G., et al. (2012). Canadian Journal of Neurological Sciences, 39(2 Suppl 2), S1-S59.
  7. Zeng, Z., Li, Y., Lu, S., et al. (2019). Acta Neurologica Scandinavica, 139(3), 284-293.
  8. Safarinejad, M.R., Safarinejad S, Shafiei, N., et al. (2012). Journal of Urology, 188(2), 526-531.
  9. Yoritaka, A., Kawajiri, S., Yamamoto, Y., et al. (2015). Parkinsonism & Related Disorders, 21(8), 911-916.
  10. Littarru, G.P., Tiano, L., Belardinelli, R., et al. (2011). BioFactors, Wiley Online Library.
  11. Qu, H., Guo, M., Chai, H., et al. (2018). Journal of the American Heart Association, 7(19), e009835.
  12. Xu, Y., Nisenblat, V., Lu, C., et al. (2018). Reproductive Biology and Endocrinology, 16(1), 29.
  13. Claessens, A.J., Yeung, C.K., Risler, L.J., et al. (2016). Annals of Clinical Biochemistry, 3(Pt 2), 265–273.
  14. Langsjoen, P.H., & Langsjoen, A.M. (2014). Clinical Pharmacology in Drug Development, 3(1), 13-17.
  15. Failla, M.L., Chitchumroonchokchai, C., & Aoki, F. (2014). Journal of Agricultural and Food Chemistry, 62(29), 7174-7182.
  16. Zhang, Y., Liu, J., Chen, X.Q., et al. (2018). Food & Function, 9(11), 5653–5659.
  17. Parikh, M., Maddaford, T.G., Austria, J.A., et al. (2019). Nutrients, 11(5), 1171. 
  18. Bonakdar, R.A., & Guarneri, E. (2005). American Family Physician, 72(6), 1065-1070.