12 Billion Active Cells† 12 Gastric Resistant Strains

60 Vegetarian Capsules ( SKU: 9456U )


  • A multi-strain blend which helps contribute to a healthy gut flora, approximating the composition of normal intestinal flora to help support a healthy intestinal tract*
  • Each strain is resistant to gastric acidity as well as high-bile concentrations*
  • Has eight human origin strains, three dairy, and one vegetable origin strain
  • At least 12 billion CFU per capsule at expiry date (guaranteed minimum 18 billion active cells at manufacturing date) 
  • Includes prebiotic FOS (fructooligosaccharides) inulin to support healthy probiotic growth*

Feature Summary

The microbial ecosystem in the gastrointestinal (GI) tract has emerged as a “virtual organ system,” with growing recognition of its diverse significance in health maintenance.*1 GI microbiota help support and maintain healthy innate and cell-mediated immune systems.2* They also help maintain the integrity of a healthy intestinal barrier by helping detoxify the body’s natural toxins and organizing the body’s response to cellular debris.*3 In addition to helping in the maintenance of gastrointestinal health, it may also help support a healthy body weight and normal glucose metabolism already within the normal range.*4,5,6,7

Probiotics have diverse functions in health support, by modulating a normal immune response and maintaining normal, healthy intestinal barrier functions.* Mixtures of probiotics appear to have additional benefits over single strains, perhaps because of synergistic function.*8,9,10,11

Probiotic-Pro 12 has 12 bacterial species, each carefully selected to withstand both gastric acid and high-bile concentrations, and for their benefits in health support.*

†Requires refrigeration for maximum potency.

Supplement Facts:


1 capsule 3 times per day on a full stomach or as directed by a health care professional.


Contains no artificial preservatives, colors or sweeteners; no gluten or wheat.

Drug Interactions

No known drug interactions exist. Separation by at least 2 hours from antibiotic use may improve the efficacy of Probiotic-Pro12.

  1. Evans, J.M., Morris, L.S., Marchesi, J.R. (2013). J Endocrinol, 218(3), R37-47.
  2. Giorgetti, G., Brandimarte, G., Fabiocchi, F., et al. (2015). Journal of Immunology Research, 2015, 501361.
  3. Ng, S.C., Hart, A.L., Kamm, M.A. (2009). Inflamm Bowel Dis, 15(2), 300-10.
  4. Ley, R.E., Turnbaugh, P.J., Klein, S., et al. (2006). Nature, 444(7122), 1022-3.
  5. Othman, M., Agüero, R., Lin, H.C. (2008). Curr Opin Gastroenterol, 24(1), 11-6.
  6. Sanz, Y., Moya-Pérez, A. (2014). Adv Exp Med Biol, 817, 291-317.
  7. Vieira, S.M., Pagovich, O.E., Kriegel, M.A. (2014). Lupus, 23(6), 518-26.
  8. Williams, E.A., Stimpson, J., Wang, D., et al. (2009). Aliment Pharmacol Ther, 29(1), 97-103.
  9. Khalesi, S., Sun, J., Buys, N., et al.(2014). Hypertension, 64(4), 897-903.
  10. Chapman, C.M., Gibson, G.R., Rowland, I. (2012). Anaerobe, 18(4), 405-13.
  11. Timmerman, H.M., Koning. C.J., Mulder, L., et al. (2004). Int J Food Microbiol, 96(3), 219-33.