OptiMega-3® Q10

OptiMega-3® Q10

900 mg Omega-3 EPA/DHA • CoQ10 100 mg

900 mg / 100 mg

60 Enteripure® Softgels ( SKU: 9322U )


  • Optimal 2:1 ratio EPA to DHA 
  • 600 mg of EPA, 300 mg of DHA, and 100 mg of CoQ10 per softgel
  • Pharmaceutical-grade omega-3 blend, standardized to meet and exceed USP standards for quality and consistency
  • Targeted delivery using a technology that embeds pure and natural ingredients into the softgel casing to prevent them from breaking down in the stomach, ensuring no fishy aftertaste
  • Safe from lipid peroxides and environmental pollutants, including heavy metals, pesticides, dioxins, PCBs, and other harmful compounds
  • Sourced from wild anchovies, sardines, and/or mackerel, some of the best natural sources of EPA and DHA
  • Harvested through sustainable fishing practices

Feature Summary

This comprehensive combination of CoQ10 and the omega-3 fatty acids EPA/DHA supports normal cognitive function and helps maintain cardiovascular health.* Both CoQ10 and EPA/DHA help maintain endothelial function, support healthy arteries, help maintain blood pressure already within the normal range, and support overall cardiovascular health.*1–5 

CoQ10 has an instrumental role in oxidative phosphorylation and mitochondrial bioenergetics, critical to neuronal health and supporting the mitochondrial function that underlies numerous facets of health, including neurological health.*6 Additionally, recent data highlights CoQ10’s emerging role in helping to organize the body’s response to cellular damage, clear cellular debris, maintain healthy insulin sensitivity, and support neurocognitive function.*7–9 Meta-analyses of randomized trials have shown that CoQ10 and EPA/DHA supplementation may help support normal levels of C-reactive protein, TNF-alpha, and IL-6.*10–12 CoQ10 serum levels have also been associated with neurological and neurocognitive support.*13,14

OptiMega-3 Q10 also has beneficial-strength pharmaceutical-grade EPA/DHA, shown to support both cardiac and vascular health, including arterial health.*15–19 Omega-3 fatty acids have been associated to help maintain myocardial and ventricular health, in addition to help organize the body’s response to cellular damage.*20–23 EPA/DHA support cognitive function through multiple mechanisms, as both are indispensable to neuronal membranes, and to help support neurological and neurocognitive health.*24,25

Supplement Facts:


Suggested Usage: 1 softgel 1–3 times per day or as directed by a health care professional.


Contains no artificial colors, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, soy, corn, egg, shellfish, salt, tree nuts, or GMOs.

Drug Interactions

Because fish oil may have  an antithrombotic effect, caution is advised for those on anticlotting, antiplatelet, or anticoagulant medications, or those at high risk of bleeding. However, a multinational randomized and controlled trial found that fish oil did not increase perioperative bleeding.26,27 In amounts greater than 3 g per day, hyperglycemia has been observed in diabetics and those with hypertriglyceridemia, close monitoring of patients on antidiabetic medication is recommended.28 CoQ10 resembles vitamin K structurally, and there is a potential interaction possible for those taking the anticoagulant Coumadin. Close monitoring of the INR is recommended with CoQ10 introduction in these patients.

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2.    Zehr, K.R., & Walker, M.K. (2018). Prostaglandins Other Lipid Mediat, 134, 131-40.

3.    Colussi, G., Catena, C., Novello, M., et al. (2017). Nutr Metab Cardiovasc Di, 27(3), 191-200.

4.    Gao, L., Mao, Q., Cao, J., et al. (2012). Atherosclerosis, 221(2), 311-6.

5.    Rosenfeldt, F.L., Haas, S.J., Krum, H., et al. (2007). J Hum Hypertens, 21(4), 297-306.

6.    Du, H., & Yan, S.S. (2010). Int J Biochem Cell Biol, 42(5), 560-72.

7.    Farsi, F., Mohammadshahi, M., Alavinejad, P., et al. (2016). J Am Coll Nutr, 35(4), 346-53.

8.    de la Monte, S.M., & Tong, M. (2014). Biochem Pharmacol, 88(4), 548-59.

9.    Yates, K.F., Sweat, V., Yau, P.L., et al. (2012). Arterioscler Thromb Vasc Biol, 32(9), 2060-7.

10.  Farsi, F., Heshmati, J., Keshtkar, A., et al. (2019). Pharmacol Res, 148, 104290.

11.  Li, K., Huang, T., Zheng, J., et al. (2014). PLoS One, 9(2), e88103. Published 2014 Feb 5.

12.  Molfino, A., Amabile, M.I., Monti, M., et al. (2017). Oxid Med Cell Longev, 2017, 5987082.

13.  Simani, L., Ryan, F., Hashemifard, S., et al. (2018). J Mol Neurosci, 66(1), 53-8.

14.  Yamagishi, K., Ikeda, A., Moriyama, Y., et al. (2014). Atherosclerosis, 237(2), 400-3.

15.  Delgado-Lista, J., Perez-Martinez, P., Lopez-Miranda, J., et al. (2012). Br J Nutr, 107 Suppl 2, S201-13.

16.  Pischon, T., Hankinson, S.E., Hotamisligil, G.S., et al. (2003). Circulation, 108(2), 155-60.

17.  Swanson, D., Block, R., & Mousa, S.A. (2012). Adv Nutr, 3, 1-7.

18.  Wang, C., Harris, W.S., Chung, M., et al. (2006. Am J Clin Nutr, 84(1), 5-17.

19.  Saito, Y., Yokoyama, M., Origasa, H., et al. (2008). Atherosclerosis, 200(1), 135-40.

20.  Pottala, J.V., Garg, S., Cohen, B.E., et al. (2010). Circ Cardiovasc Qual Outcomes, 3(4), 406-12.

21.  Casula, M., Soranna, D., Catapano, A.L., et al. (2013). Atheroscler Suppl, 14(2), 243-51.

22.  Tanaka, K., Ishikawa, Y., Yokoyama, M., et al. (2008). Stroke, 39(7), 2052-8.

23.  Heydari, B., Abdullah, S., Pottala, J.V., et al. (2016). Circulation, 134(5), 378-91.

24.  Lin, P.Y., Chiu, C.C., Huang, S.Y., et al. (2012). J Clin Psychiatry, 73(9), 1245-54.

25.  Dyall, S.C. (2015). Front Aging Neurosci, 7, 52.

26.  Harris, W.S. (2007). Am J Cardiol. 99(6A), 44C-6C.

27.  Akintoye, E., Sethi, P., Harris, W.S., et al. (2018). Circ Cardiovasc Qual Outcomes, 11(11), e004584.

28. Gao, H., Geng, T., Huang, T., & Zhao, Q. (2017). Lipids in health and disease, 16(1), 131.