Magnesium Bisglycinate

Magnesium Bisglycinate

Maintains Proper Muscle Function* Supports Metabolism*

200 mg

4.2 oz Powder ( SKU: 9500U )

Benefits

  • Magnesium bisglycinate form is more easily absorbed than salt forms such as magnesium oxide1*
  • Bisglycinate chelated form is less likely to cause temporary diarrhea than salt forms1,2*
  • Powder form allows for easy and convenient use without food
  • Non-GMO and suitable for vegetarians/vegans
  • Sugar free with pleasant taste from citric acid

Feature Summary

Magnesium bisglycinate is magnesium bound to the amino acid glycine. Magnesium is an important factor in routine muscle mass and repair.3* It also supports healthy metabolism, the ability to derive energy from proteins, carbohydrates, and fat.4* It helps maintain cardiovascular health by supporting healthy blood pressure already within the normal range, and helps maintain healthy insulin sensitivity and support plasma glucose levels already within the normal range.5,6* Magnesium needs can be increased by occasional stress, a temporarily unbalanced diet, coffee, and occasional alcohol consumption.7

Magnesium is the fourth most common mineral ion in the body and the second most common in cells, contributing to the health of both cardiac and skeletal muscles as well as the generation of ATP.8,9* It also contributes to nerve impulse transmission and bone mineralization.10,11* Magnesium may help maintain healthy muscle function throughout the lifespan, supporting healthy aging.12* The bisglycinate form is more efficiently absorbed than the more common oxide form.1

Supplement Facts:

Allergens:

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Dosage:

Suggested Usage: Mix 1 scoop (2.4 g) into water or juice once per day or as directed by a health care professional.

Drug Interactions

When taken together, magnesium can decrease the absorption of levodopa/carbidopa,14 quinolone antibiotics,15 and tetracycline antibiotics,16 and can increase the absorption of sulfonylureas.17 Magnesium levels may be depleted by aminoglycoside antibiotics18 amphotericin B,19 cyclosporine,20 digoxin,21 potassium-wasting diuretics, oral contraceptives,22 foscarnet,23 sodium phosphates,24 tacrolimus,25 and proton-pump inhibitors.9

1. Schuette, S. A., Lashner, B. A., & Janghorbani, M. (1994). Journal of Parenteral and Enteral Nutrition, 18(5), 430-435.
2. Siebrecht, S. (2013). OM & Ernahrung, 144.
3. Welch, A. A., Kelaiditi, E., Jennings, A., et al. (2016). Journal of Bone and Mineral Research, 31(2), 317-325.
4. Jahnen-Dechent, W., & Ketteler, M. (2012). Clinical Kidney Journal, 5(Suppl 1), i3-i14.
5. Verma, H., & Garg, R. (2017). Journal of Human Nutrition and Dietetics: The Official Journal of the British Dietetic Association, 30(5), 621-633.
6. Rodríguez-Morán, M., Simental-Mendía, L. E., Gamboa-Gómez, C. I., et al. (2018).
Advances in Chronic Kidney Disease, 25(3), 261-266.
7. Nechifor, M. (2018). Magnesium Research, 31(3), 90-98.
8. de Baaij, J. H., Hoenderop, J. G., & Bindels, R. J. (2015). Physiological Reviews, 95(1), 1-46.
9. Glasdam, S. M., Glasdam, S., & Peters, G. H. (2016). Advances in Clinical Chemistry, 73, 169-193.
10. Gröber, U., Schmidt, J., & Kisters, K. (2015). Nutrients, 7(9), 8199-8226. 11. Razzaque, M. S. (2018). Nutrients, 10(12), 1863.
12. Veronese, N., Berton, L., Carraro, S., et al. (2014). American Journal of Clinical Nutrition, 100(3), 974-981.
13. Van Laecke, S. (2019). Acta Clinica Belgica, 74(1), 41-47.
14. Kashihara, Y., Terao, Y., Yoda, K., et al. (2019). European Journal of Clinical Pharmacology, 3, 351.
15. Imaoka, A., Hattori, M., Akiyoshi, T., et al. (2014). Drug Metabolism and Pharmacokinetics, 29(5), 414-418.
16. Sompolinsky, D., & Samra, Z. (1972). Journal of Bacteriology, 110(2), 468-476.
17. Neuvonen, P., & Kivisto, K. (1991). British Journal of Clinical Pharmacology, 32(2), 215.
18. L’Hommedieu, C. S., Nicholas, D., Armes, D. A., et al. (1983). The Journal of Pediatrics, 102(4), 629-631.
19. Karimzadeh, I., Heydari, M., Ramzi, M., et al. (2016). Nephro-Urology Monthly, 8(5), e39581.
20. Thompson, C. B., June, C. H., Sullivan, K. M., et al. (1984). Lancet, 2(8412), 1116-1120.
21. Gottlieb, S. S., Baruch, L., Kukin, M. L., et al. (1990). Journal of the American College of Cardiology, 16(4), 827.
22. Palmery, M., Saraceno, A., Vaiarelli, G., et al. (2013). European Review for Medical and Pharmacological Sciences, 17(13), 1804-1813.
23. Huycke, M. M., Naguib, M. T., Stroemmel, M. M., et al. (2000). Antimicrobial Agents and Chemotherapy, 44(8), 2143-2148.
24. Shaoul, R., Wolff, R., Seligmann, H., et al. (2001). Gastrointestinal Endoscopy, 53(6), 650-652.
25. Gratreak, B. D., Swanson, E. A., Lazelle, R. A., et al. (2020). Physiological Reports, 8(1), e14316.