Digest-ProGD® HP

Digest-ProGD® HP

Supports Gluten and Dairy Digestion*

295 mg

60 Vegetarian Capsules ( SKU: 9503U )


  • Includes fungal and bacterial proteases to support normal hydrolysis of difficult-to-digest proline-containing peptides, such as gluten and casein*
  • Supports comprehensive carbohydrate digestion with plant-based papain, bromelain, and fungal digestive enzymes*
  • Nearly 300 mg enzyme blend delivered in each vegetarian capsule allows for easy dosing*
  • Completely suitable for vegetarians

Feature Summary

Digest-ProGD HP is a proprietary enzyme blend for comprehensive carbohydrate digestive support.* It includes fungal proteases derived from Aspergillus oryzae, bacterial protease derived from Bacillus subtilis, and comprehensive carbohydrate digestive support from papain, bromelain, and fungal digestive enzymes.* Aspergillus oryzae extracts are sources of prolyl endopeptidases and dipeptidyl peptidase IV (DPP-IV) – a multifunctional serine protease suitable for proline-containing peptides, such as those found in gliadin and casein, both typically proteolytically resistant proteins.*1–4

Protease activity from Aspergillus oryzae supports normal protease activity at the proline-rich 33-mer of gliadin.*5 The proline-rich proteins found in gluten are thought to facilitate a cellular debris-generating response in individuals with gluten sensitivity or for whom gluten is problematic, often because of accidental gluten exposure, even for those on a gluten-free diet.*6 According to animal studies, supplementation with protease from Aspergillus oryzae may support a bifidogenic effect, maintaining normal bifidobacteria in the intestines as well as supporting healthy gut-protective amino acids.*7,8

In addition to fungal and bacterial proteases, Digest-ProGD HP includes alpha-amylase, cellulose, and hemicellulose for comprehensive carbohydrate digestion support.*

Supplement Facts:


Suggested Usage: 1 capsule 3 times per day with meals or as directed by a health care professional. Consult a health care professional for prolonged use.


Contains no artificial colors, preservatives, or sweeteners; no sugar, wheat, gluten, yeast, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

1. Mulvihill, E.E., & Drucker, D.J. (2014). Endocr Rev, 35(6), 992-1019.
2. Nongonierma, A.B., & FitzGerald, R.J. (2014). Food Chem, 145, 845-52.
3. Lambeir, A.M., Durinx, C., Scharpé, S., et al. (2003). Crit Rev Clin Lab Sci, 40(3), 209-94.
4. Pourmohammadi, K., & Abedi, E. (2021). Food Sci Nutr, 9(7), 3988-4006.
5. Eugster, P.J., Salamin, K., Grouzmann, E., et al. (2015). Microbiol, 161(12), 2277-88.
6. Cerf-Bensussan, N., Matysiak-Budnik, T., Cellier, C., et al. (2007). Gut, 56(2), 157-60.
7. Yang, Y., Iwamoto, A., Kumrungsee, T., et al. (2017). Nutr Res, 44, 60-6.
8. Yang, Y., Kumrungsee, T., Kuroda, M., et al. (2019). Biosci Biotechnol Biochem, 83(10), 1901-11.