PCOS Care®

PCOS Care®

Provides Recommended 40:1 Ratio of Myo to D-Chiro Inositol

129 g ( SKU: 9676, NPN: 80087737 )

Benefits

  • Provides recommended 40 to ?1 ratio of myo to D-chiro inositol
  • Contains naturally occurring forms of inositol, clinically shown to have complementary effects on both metabolic and ovarian function among women with PCOS
  • Includes methylcobalamin and activated folate (L-5-MTHF) for optimal fertility and pregnancy outcomes
  • Unflavoured powder allows for easy twice-per-day dosing

Feature Summary

PCOS CARE® provides the two most common, naturally occurring, and complementary forms of inositol, clinically shown to improve both ovarian and metabolic function in women with polycystic ovarian syndrome (PCOS). Many clinical trials with myo-inositol have shown a positive effect on spontaneous ovulation and on human oocyte meiotic maturation and quality, as well as improvements in metabolic risk factors and reductions in androgen levels among women with PCOS. In a recent meta-analysis of seven trials, myo-inositol was shown to increase pregnancy rates among subfertile women undergoing ovulation induction for ICSI or IVF-ET, as well as to reduce the number of unsuitable oocytes and ovulation medications needed.

Similarly, D-chiro-inositol has been shown to improve ovarian function and metabolism, including improvements in cycle regularity, blood pressure, HOMA index, and hormones such as insulin and LH. In PCOS Care, these complementary nutrients are combined in the 40:1 ratio that has been shown to improve metabolic symptoms and IVF outcomes among women with PCOS more effectively than myo-inositol alone, and at the dosing ratio recommended by the International Consensus Conference on myo-inositol and D-chiro-Inositol.

Medicinal Ingredients

Each Serving (2.15 g) Contains:
Myo-inositol 2 g
D-chiro-inositol 50 mg
Folate (L-5-Methyltetrahydrofolate, calcium salt) 200 mcg
Vitamin B12 (Methylcobalamin) 1.5 mcg

Non-Medicinal Ingredients

Organic Oryza sativa (rice) hull powder.

Dosage:

Recommended Adult Dose: 1 serving (2.15 g) twice daily dissolved in 250 mL of water or as directed by a health care practitioner.

Warnings:

Consult a health care practitioner prior to use if you are pregnant or breastfeeding, or to ensure a timely treatment of a serious cause of infertility. Consult a health care practitioner if symptoms persist or worsen. Keep out of reach of children.

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

No known contraindications.

Drug Interactions

Myo-inositol has been shown to enhance the efficacy of clomiphene. When given with folic acid, it improved ovulation rates (65.5%) compared to clomiphene alone (42%), as well as pregnancy rates (53.8% combined use vs. 42.2% clomiphene alone).  Medication dosage to control hyperglycemia may need monitoring, as myo-inositol has benefits on insulin sensitivity similar to metformin.

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  2. Regidor PA, Schindler AE, Lesoine B, et al. Management of women with PCOS using myo-inositol and folic acid. New clinical data and review of the literature. Horm Mol Biol Clin Investig. 2018; 34(2). Pii PMID: 29498933.
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