Liposomal Vitamin C

Liposomal Vitamin C

Optimized Absorption

1000 mg per serving

90 Softgels ( SKU: 9412, NPN: 80121161 )


  • 1000 mg of vitamin C per two-softgel serving
  • Liposomes encapsulate vitamin C in a highly bioavailable lipid bilayer, exceeding plasma levels with standard supplements
  • Liposomes increase both the peak plasma levels and total vitamin C absorption
  • Gentle form of vitamin C
  • Potent antioxidant, also providing immune, collagen, and bone support
  • Non-GMO and gluten-free

Feature Summary

Liposomal Vitamin C is a highly bioavailable form of this essential antioxidant known to protect against oxidative damage, support healthy immune function, and play an essential role in collagen synthesis. Vitamin C is a cofactor for prolyl and lysyl hydroxylases, enzymes needed for collagen development in joints and bones. A higher intake of vitamin C has been associated with a reduced risk for osteoporotic fracture and an increase in bone mineral density. 1,2 Vitamin C increases iron absorption, stabilizes vitamin E and folic acid, and attenuates inflammation. 3,4 A greater risk for deficiency has been identified in a number of populations, including older adults, individuals with inflammatory bowel disease, cancer, or food allergies, and tobacco smokers. 4 Vitamin C supplementation enhances immune function and is associated with a shorter duration of respiratory tract infections, such as the common cold. 5 Supplementation has also been associated with improved liver function and glycemic control in non-alcoholic fatty liver disease (NAFLD). 6,7

Liposomes encapsulate vitamin C in a phospholipid bilayer, bypassing typical limitations of absorption and increasing plasma ascorbic acid levels to a greater degree than typical supplementation. 8,9 Liposomal forms of vitamin C have been shown to nearly double the bioavailability while retaining the safety of standard ascorbic acid supplementation. 10

Medicinal Ingredients

Each Softgel Contains:
Vitamin C (ascorbic acid, sodium ascorbate) 500 mg

Non-Medicinal Ingredients

Softgel (gelatin, glycerin, purified water, carob powder), flaxseed oil, phospholipids, yellow beeswax.


Recommended Dose (Adolescents 9–18 Years and Adults 18 Years and Older): 2 softgels daily or as directed by a health care practitioner.


Keep out of reach of children.


Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, egg, fish, shellfish, tree nuts, or GMOs. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.


Vitamin C supplementation is contraindicated in blood disorders such as thalassemia, glucose-6-phosphate dehydrogenase (G6PD) deficiency, sickle cell disease, and hemochromatosis. Vitamin C should be used cautiously in oxalate nephropathy or nephrolithiasis, as acidification by ascorbic acid increases the chances of precipitation of cysteine, urate, and oxalate stones, particularly in men.4,11

Drug Interactions

No known contraindications. Some medications deplete vitamin C, and supplementation may mitigate adverse effects, including aspirin, indomethacin, oral contraceptives, tetracyclines, and corticosteroids.4

  1. Malmir, H., Shab-Bidar, S., & Djafarian, K. (2018). Vitamin C intake in relation to bone mineral density and risk of hip fracture and osteoporosis: A systematic review and meta-analysis of observational studies. Br J Nutr, 119(8), 847-58.
  2. Aghajanian, P., Hall, S., Wongworawat, M.D., et al. (2015). The roles and mechanisms of actions of vitamin C in bone: New developments. J Bone Miner Res, 30(11), 1945-55.
  3. Ellulu, M.S. (2017). Obesity, cardiovascular disease, and role of vitamin C on inflammation: A review of facts and underlying mechanisms. Inflammopharmacology, 25(3), 313-28.
  4. Abdullah, M., Jamil, R.T., & Attia, F.N. (2022). Vitamin C (ascorbic acid). StatPearls [Internet].
  5. Keya, T.A., Leela, A., Fernandez, K., et al. (2022). Effect of vitamin C supplements on respiratory tract infections: A systematic review and meta-analysis. Curr Rev Clin Exp Pharmacol, 17(3), 205-15.
  6. He, Z., Li, X., Yang, H., et al. (2021). Effects of oral vitamin C supplementation on liver health and associated parameters in patients with non-alcoholic fatty liver disease: A randomized clinical trial. Front Nutr, 8, 745609.
  7. Ashor, A.W., Werner, A.D., Lara, J., et al. (2017). Effects of vitamin C supplementation on glycaemic control: A systematic review and meta-analysis of randomised controlled trials. Eur J Clin Nutr, 71(12), 1371-80.
  8. Davis, J.L., Paris, H.L., Beals, J.W., et al. (2016). Liposomal-encapsulated ascorbic acid: Influence on vitamin C bioavailability and capacity to protect against ischemia-reperfusion injury. Nutr Metab Insights, 9, 25-30.
  9. Prantl, L., Eigenberger, A., Gehmert, S., et al. (2020). Enhanced resorption of liposomal packed vitamin C monitored by ultrasound. J Clin Med, 9(6), 1616.
  10. Gopi, S., & Balakrishnan, P. (2021). Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res, 31(4), 356-64.
  11. Jiang, K., Tang, K., Liu, H., et al. (2019). Ascorbic acid supplements and kidney stones incidence among men and women: A systematic review and meta-analysis. Urol J, 16(2), 115-20.