GI Care

GI Care

Mango – Passion Fruit

120 g Mango – Passion Fruit ( SKU: 9631, NPN: 80131494 )

Benefits

  • Botanicals and nutrients that promote a healthy gastrointestinal lining, providing protection against GI injury and improving intestinal permeability
  • Phytochemicals and zinc carnosine stimulate intestinal repair and protect against damage, restoring healthy intestinal barrier function
  • Used in herbal medicine to help relieve inflammatory conditions of the gastrointestinal tract and mild digestive upset
  • Clinically relevant doses of each active ingredient
  • Powder allows for flexible dosing and administration
  • Delicious mango-passionfruit flavour
  • Suitable for vegetarians/vegans

Medicinal Ingredients

Each Scoop (Approx. 4 g) Contains:
Deglycyrrhizinated Licorice 10:1 Extract (Glycyrrhiza glabra) (root) 1200 mg
Chamomile 4:1 Extract (Matricaria chamomilla) (flower) 400 mg
Marshmallow 4:1 Extract (Althaea officinalis) (root) 600 mg
Zinc L-Carnosine (Polaprezinc) 150 mg
Aloe (Aloe vera) (leaf gel) 600 mg

Non-Medicinal Ingredients

Natural flavours, citric acid, guar gum, DL-malic acid, stevia leaf extract, Oryza sativa (rice) hull powder.

Dosage:

Recommended Adult Dose: Take 1 scoop (approx. 4 g) once daily or as directed by a health care practitioner. Mix with liquid before use. Take with food, a few hours before or after taking other medications or natural health products.

Warnings:

Ask a health care practitioner before use if you are pregnant or breastfeeding. Ask a health care practitioner before use if you have diabetes. Zinc supplementation can cause a copper deficiency. If you are unsure whether you are taking enough copper, consult a health care practitioner prior to use. Ask a health care practitioner if symptoms persist or worsen. Stop use if hypersensitivity/allergy occurs. Keep out of reach of children.

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Contraindications

Avoid use with a known hypersensitivity to any of the ingredients, including allergies to aloe or members of the daisy (Asteraceae) family.

Drug Interactions

No clearly established interactions, but caution is advised while using sedative medications, as there is a theoretical additive effect with chamomile.18 Licorice may cause hypertension and hypokalemia, and interact with anticoagulants in animal models, due to glycyrrhizic acid activity.19 Thus, while unlikely to occur with DGL as glycyrrhizic acid has been removed, use should be carefully monitored in these patients.

1.     Turpie, A.G., Runcie, J., & Thomson, T.J. (1969). Clinical trial of deglydyrrhizinized liquorice in gastric ulcer. Gut, 10(4), 299-302.

2.     Yang, R., Wang, L.Q., Yuan, B.C., et al. (2015). The pharmacological activities of licorice. Planta Med, 81(18), 1654-69.

3.     Morgan, A.G., McAdam, W.A., Pacsoo, C., et al. (1982). Comparison between cimetidine and Caved-S in the treatment of gastric ulceration, and subsequent maintenance therapy. Gut, 23(6), 545-51.

4.     Wittschier, N., Faller, G., & Hensel, A. (2009). Aqueous extracts and polysaccharides from liquorice roots (Glycyrrhiza glabra L.) inhibit adhesion of Helicobacter pylori to human gastric mucosa. J Ethnopharmacol, 125(2), 218-23.

5.     Sah, A., Naseef, P.P., Kuruniyan, M.S., et al. (2022). A comprehensive study of therapeutic applications of chamomile. Pharmaceuticals (Basel), 15(10), 1284.

6.     Jabri, M.A., Hajji, N., Wannes, D., et al. (2017). HPLC/PDA/ESI-MS/MS analysis of chamomile decoction and mechanism of its protective effects on aspirin-induced small bowel injuries. RSC Adv, 7, 53472-80.

7.     Sadighara, P., Gharibi, S., Moghadam Jafari, A., et al. (2012). The antioxidant and flavonoids contents of Althaea officinalis L. flowers based on their color. Avicenna J Phytomed, 2(3), 113-7.

8.     Albahri, G., Badran, A., Hijazi, A., et al. (2023). The therapeutic wound healing bioactivities of various medicinal plants. Life (Basel), 13(2), 317.

9.     Deters, A., Zippel, J., Hellenbrand, N., et al. (2010). Aqueous extracts and polysaccharides from marshmallow roots (Althea officinalis L.): Cellular internalisation and stimulation of cell physiology of human epithelial cells in vitro. J Ethnopharmacol, 127(1), 62-9.

10.   Le Phan, T.H., Park, S.Y., Jung, H.J., et al. (2021). The role of processed aloe vera gel in intestinal tight junction: An in vivo and in vitro study. Int J Mol Sci, 22(12), 6515.

11.   Zhang, D., Zhou, X., Liu, L., et al. (2021). Glucomannan from aloe vera gel promotes intestinal stem cell-mediated epithelial regeneration via the Wnt/β-Catenin pathway. J Agric Food Chem, 69(36), 10581-91.

12.   Jiang, H., Shi, G.F., Fang, Y.X., et al. (2022). Aloin A prevents ulcerative colitis in mice by enhancing the intestinal barrier function via suppressing the Notch signaling pathway. Phytomedicine, 106, 154403.

13.   Langmead, L., Feakins, R.M., Goldthorpe, S., et al. (2004). Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis. Aliment Pharmacol Ther, 19(7), 739-47.

14.   Størsrud, S., Pontén, I., & Simrén, M. (2015). A pilot study of the effect of aloe barbadensis mill. extract (AVH200®) in patients with irritable bowel syndrome: A randomized, double-blind, placebo-controlled study. J Gastrointestin Liver Dis, 24(3), 275-80.

15.   Efthymakis, K., & Neri, M. (2022). The role of Zinc L-Carnosine in the prevention and treatment of gastrointestinal mucosal disease in humans: A review. Clin Res Hepatol Gastroenterol, 46(7), 101954.

16.   Watari, I., Oka, S., Tanaka, S., et al. (2013). Effectiveness of polaprezinc for low-dose aspirin-induced small-bowel mucosal injuries as evaluated by capsule endoscopy: A pilot randomized controlled study. BMC Gastroenterol, 13, 108.

17.   Mahmood, A., FitzGerald, A.J., Marchbank, T., et al. (2007). Zinc carnosine, a health food supplement that stabilises small bowel integrity and stimulates gut repair processes. Gut, 56(2), 168-75.

18.   McKay, D.L., & Blumberg, J.B. (2006). A review of the bioactivity and potential health benefits of chamomile tea (Matricaria recutita L.). Phytother Res, 20(7), 519-30.

19.   AlDehlawi, H., & Jazzar, A. (2023). The power of Licorice (Radix glycyrrhizae) to improve oral health: A comprehensive review of its pharmacological properties and clinical implications. Healthcare (Basel), 11(21), 2887.