BioFoundation-G™

BioFoundation-G™

Multiple Vitamin & Mineral Formula

180 Tablets ( SKU: 9476, NPN: 80051438 )

Benefits

  • A full spectrum of vitamins and minerals
  • Provides rate-limiting nutrients for glutathione production, necessary for xenobiotic detoxifi cation
  • Contains clinical doses of resveratrol, lipoic acid, CoQ10, milk thistle, and green tea extract
  • Broad-spectrum antioxidant support, including bilberry and citrus extracts, lipoic acid, lycopene, and lutein
  • Highly bioactive and bioavailable nutrients, such as pyridoxal-5-phosphate and vitamin K2 (Menaquinone 7)

Feature Summary

BioFoundation-G is a comprehensive vitamin and mineral supplement to support healthy living in the modern world. A broad-spectrum and highly bioavailable multivitamin and mineral, BioFoundation-G’s formulation uses clinically driven research to provide the nutritional foundation needed for the modern environment. This complete multivitamin and mineral formula contains clinical doses of nutrients such as N-acetyl-cysteine and R-alpha-lipoic acid, well established to increase cellular levels of glutathione, the most prevalent intercellular antioxidant. Glutathione is one of the most important conjugators of numerous environmental and endogenous toxins. It is known to be depleted not only by xenobiotics, but also by chronic conditions such as inflammatory and neurodegenerative diseases. 

Glutathione support is linked to lower rates of cell death and apoptosis. BioFoundation-G provides physiologically relevant doses of hepatoprotectors such as milk thistle, antioxidants, mitochondrial bioenergetic enhancers such as CoQ10, and co-factors for critical detoxifi cation enzymes. It also provides the biological modifiers natural transresveratrol and green tea phytosome, two nutrients shown to have anti-inflammatory, weight management, anti-aging, cardiovascular, and stress-related benefits.

Medicinal Ingredients

Each Tablet Contains: Daily Dose:
Vitamin A (Palmitate) 500 IU (150 mcg RAE) 1500 IU (450 mcg RAE) 
Vitamin B1 (Thiamine Hydrochloride) 4.2 mg 12.6 mg 
Vitamin B2 (Riboflavin) 4.2 mg 12.6 mg 
Vitamin B3 (Niacin) 12.5 mg 37.5 mg 
Vitamin B3 (Niacinamide) 33.3 mg 100 mg 
Vitamin B5 (Pantothenic Acid) (Calcium d-Pantothenate) 16.7 mg 50 mg 
Vitamin B6 (Pyridoxine Hydrochloride) (Pyridoxal 5-Phosphate) 2.5 mg 7.5 mg 
Biotin 8.3 mcg 25 mcg 
Betaine Hydrochloride 16.7 mg 50 mg 
Folate (from (6S)-5-Methyltetrahydrofolic Acid (MTHF), Glucosamine Salt, Quatrefolic®) 83 mcg 249 mcg 
Vitamin B12 (Methylcobalamin) 167 mcg 501 mcg 
Para-Aminobenzoic Acid (PABA) 4.2 mg 12.6 mg 
Choline (Bitartrate) 4.2 mg 12.6 mg 
Inositol 4.2 mg 12.6 mg 
Vitamin C (Ascorbic Acid) 167 mg 501 mg 
Vitamin D3 (Cholecalciferol) 333 IU (8.3 mcg) 999 IU (25 mcg) 
Vitamin E (d-Gamma Tocopherol) 33.3 mg 100 mg 
Vitamin K2 (Menaquinone) (MK-7) (Natto Bean) 7.5 mcg 22.5 mcg 
Boron (Citrate) 41.7 mcg 125 mcg 
Calcium (HVP* Chelate) 16.7 mg 50 mg 
Chromium (Polynicotinate) 33.3 mcg 100 mcg 
Copper (HVP* Chelate) 170 mcg 510 mcg 
Iodine (Ascophyllum nodosum) (whole plant) 50 mcg 150 mcg 
Magnesium (HVP* Chelate) 33.3 mg 100 mg 
Manganese (Citrate) 0.8 mg 2.4 mg 
Molybdenum (Citrate) 66.7 mcg 200 mcg 
Potassium (Citrate) 6.8 mg 20.4 mg 
Selenium (Selenomethionine) 33.3 mcg 100 mcg 
Vanadium (Citrate) 2.5 mcg 7.5 mcg 
Zinc (Citrate) 2.5 mg 7.5 mg 
Bilberry Extract (Vaccinium myrtillus) (36% Anthocyanosides) (fruit) 6.6 mg 20 mg 
Citrus Bioflavonoids 4:1 Extract (Citrus limon, Citrus sinensis, Citrus paradisi, Citrus reticulata, Citrus aurantiifolia) (fruit) 8.3 mg 25 mg 
Coenzyme Q10 (Microorganism) (whole cell) 8.3 mg 25 mg 
Green Tea Phytosome® (Camellia sinensis, Glycine max) (13% EGCG**) (leaf, seed) 8.3 mg 25 mg 
Hesperidin (Citrus sinensis) (fruit) 4.2 mg 12.6 mg
Lutein (Tagetes erecta) (flower) 550 mcg 1650 mcg 
Lycopene (Lycopersicon esculentum) (fruit) 280 mcg 840 mcg 
Silybin Phytosome® (Silybum marianum, Glycine max) (15% Silybin) (fruit, seed) 25 mg 75 mg 
N-Acetyl-L-Cysteine 25 mg 75 mg 
R-Alpha-Lipoic Acid 41.7 mg 125 mg 
ResveratrolRich® Proprietary Blend [Wine Grape (Vitis vinifera) (fruit), Purified Japanese Knotweed (Polygonum cuspidatum) (root)] 33.3 mg 100 mg 
Providing Natural Trans-Resveratrol 16.7 mg 50 mg 
*HVP: Hydrolyzed Vegetable Protein **EGCG: epigallocatechin-3-gallate

Non-Medicinal Ingredients

Microcrystalline cellulose, croscarmellose sodium, coating (carbohydrate gum [cellulose], glycerin), vegetable grade magnesium stearate (lubricant).

Dosage:

Recommended Adult Dose: 3 tablets per day with meals, 2 hours before or after taking other medications, or as directed by a health care practitioner.

Warnings:

Consult a health care practitioner prior to use if you have diabetes, kidney stones, a liver disorder, an iron deficiency, a history of non-melanoma skin cancer, peptic ulcer, excess stomach acid, if you are pregnant or breastfeeding, or if you are taking blood thinners, sulfonamides, or blood pressure medication. Consult a health care practitioner prior to use if you are taking prescription medications, as resveratrol may alter the effectiveness of these medications. Hypersensitivity (e.g., allergy) has been known to occur, in which case discontinue use. Do not use this product if you are taking antibiotics or nitroglycerin. If you experience sweating, paleness, chills, headache, dizziness, and/or confusion, discontinue use and consult a health care practitioner (as these may be symptoms of serious low blood sugar). Stop use and consult a health care practitioner if you develop symptoms of liver trouble such as yellowing of the skin/eyes (jaundice), stomach pain, dark urine, sweating, nausea, unusual tiredness, and/or loss of appetite. Rare, unpredictable cases of liver injury associated with products containing green tea extract have been reported (in Canada and internationally). People sensitive to nicotinic acid may experience flushing of the skin that is generally mild and transient. Keep out of reach of children.

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, sugar, wheat, gluten, yeast, egg, fish, shellfish, tree nuts, or GMOs. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

Consult a health care practitioner if you are taking blood thinners, or if you are pregnant or breastfeeding. Consult a health care practitioner prior to use if you have diabetes or kidney stones, or if you are taking sulfonamides or blood pressure medication. Consult a health care practitioner prior to use if you are taking prescription medication, as resveratrol may alter the effectiveness of these medications. Hypersensitivity (e.g., allergy) has been known to occur, in which case discontinue use. Do not use this product if you are taking antibiotics or nitroglycerin. Keep out of reach of children.

Drug Interactions

Vitamin K supplementation may decrease the efficacy of warfarin, or require more close monitoring of its administration.19 This product contains nutrients known to reduce hypertension and hyperglycemia, and may require lower dosing or discontinuation of related medications.

  1. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., et al. (2007). N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency. Current opinion in pharmacology, 7(4), 355–359.
  2. Shay, K. P., Moreau, R. F., Smith, E. J., et al. (2009). Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential. Biochimica et biophysica acta, 1790(10), 1149–1160.
  3. Becker, K., Pons-Kühnemann, J., Fechner, A., et al. (2005). Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor – a pilot study. Redox Report, 10(4), 215–226.
  4. Awasthi, Y. C., Chaudhary, P., Vatsyayan, R., et al. (2009). Physiological and pharmacological significance of glutathione-conjugate transport. Journal of toxicology and environmental health. Part B, Critical reviews, 12(7), 540–551.
  5. Ludewig, G., Srinivasan, A., & Robertson, L. W. (2000). Mechanisms of toxicity of PCB metabolites: generation of reactive oxygen species and glutathione depletion. Central European journal of public health, 8 Suppl, 15–17.
  6. Ahmed, T., Tripathi, A. K., Ahmed, R. S., et al. (2008). Endosulfan-induced apoptosis and glutathione depletion in human peripheral blood mononuclear cells: Attenuation by N-acetylcysteine. Journal of biochemical and molecular toxicology, 22(5), 299–304.
  7. Lee, D. H., & Jacobs, D. R., Jr (2009). Serum gamma-glutamyltransferase: new insights about an old enzyme. Journal of epidemiology and community health, 63(11), 884–886.
  8. Ljubisavljevic, S., Stojanovic, I., Cvetkovic, T., et al. (2014). Glutathione homeostasis disruption of erythrocytes, but not glutathione peroxidase activity change, is closely accompanied with neurological and radiological scoring of acute CNS inflammation. Neuroimmunomodulation, 21(1), 13–20.
  9. Circu, M. L., & Aw, T. Y. (2012). Glutathione and modulation of cell apoptosis. Biochimica et biophysica acta, 1823(10), 1767–1777.
  10. Rosenfeldt, F., Marasco, S., Lyon, W., et al. (2005). Coenzyme Q10 therapy before cardiac surgery improves mitochondrial function and in vitro contractility of myocardial tissue. The Journal of thoracic and cardiovascular surgery, 129(1), 25–32.
  11. Kiruthiga, P. V., Shafreen, R. B., Pandian, S. K., et al. (2007). Silymarin protection against major reactive oxygen species released by environmental toxins: exogenous H2O2 exposure in erythrocytes. Basic & clinical pharmacology & toxicology, 100(6), 414–419.
  12. Wightman, E. L., Haskell-Ramsay, C., Reay, J. L., et al. (2015). The effects of chronic trans-resveratrol supplementation on aspects of cognitive function, mood, sleep, health and cerebral blood flow in healthy, young humans. The British Journal of Nutrition, 114(9), 1427­–1437.
  13. Hoseini, A., Namazi, G., Farrokhian, A., et al. (2019). The effects of resveratrol on metabolic status in patients with type 2 diabetes mellitus and coronary heart disease. Food & function, 10(9), 6042–6051.
  14. Brasnyó, P., Molnár, G. A., Mohás, M., et al. (2011). Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients. The British journal of nutrition, 106(3), 383–389
  15. Gilardini, L., Pasqualinotto, L., Di Pierro, F., et al. (2016). Effects of Greenselect Phytosome® on weight maintenance after weight loss in obese women: a randomized placebo-controlled study. BMC complementary and alternative medicine, 16, 233.
  16. Ford, S. K., Misita, C. P., Shilliday, B. B., et al. (2007). Prospective study of supplemental vitamin K therapy in patients on oral anticoagulants with unstable international normalized ratios. Journal of thrombosis and thrombolysis, 24(1), 23–27.