Betaine HCI

Betaine HCI

with Fenugreek

500 mg

60 Vegetarian Capsules ( SKU: 9229, NPN: 80053147 )

Benefits

  • Naturally sourced from beets
  • 500 mg of betaine HCl per capsule allows for flexible-dose titration
  • Suitable for vegetarians and vegans

Feature Summary

Betaine hydrochloride increases hydrochloric acid (HCl) in the stomach to enhance digestion, while the addition of fenugreek helps soothe and protect the stomach’s lining. Low stomach acid is more common with age, and may be associated with a number of health conditions. Combining betaine HCl with fenugreek may help boost digestion and soothe the digestive tract.

HCl assists in protein digestion by activating pepsinogen to pepsin, helping to inactivate orally ingested pathogens, preventing bacterial or fungal overgrowth of the small intestine, encouraging the flow of bile and pancreatic enzymes, and facilitating the absorption of several nutrients, including vitamin B12, ascorbic acid, calcium, iron, and magnesium.(1−4) However, poor digestion can arise in the absence of adequate HCl, leading to bloating, belching, indigestion, and diarrhea or constipation.(5) Numerous studies have shown acid secretion declines with advancing age (6−8), and impaired HCl production and secretion is correlated with a variety of clinical conditions.(5)While the underlying etiological factors leading to impaired or absent HCl secretion are not well understood, long-term supplementation is generally safe and may be effective in certain patient populations and clinical conditions.(9) Combining betaine HCl with fenugreek further supports digestive function and health, as fenugreek seeds are an excellent source of mucilage (10), which may help soothe gastrointestinal inflammation by coating the lining of the stomach and intestine.

Medicinal Ingredients

Each Capsule Contains:
Betaine Hydrochloride 500 mg
Fenugreek (Trigonella foenum-graecum) (seed) 100 mg

Non-Medicinal Ingredients

Vegetarian capsule (carbohydrate gum [cellulose], purified water), vegetable grade magnesium stearate (lubricant), silica.

Dosage:

3 capsules daily with 250 ml of water or as directed by a health care practitioner. Consult a health care practitioner for use beyond 12 weeks.

Warnings:

Consult a health care practitioner if you are pregnant or breastfeeding or if you experience symptoms of gastrointestinal problems . Consult a health care practitioner prior to use if you have cardiovascular disease or diabetes . Do not use if you have peptic ulcer. Keep out of reach of children .

Allergens:

Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans. Sealed for your protection. Do not use if seal is broken. For freshness, store in a cool, dry place.

Contraindications

Individuals with peptic ulcer disease (PUD) or diseases that cause excessive secretion of gastric acid, such as Zollinger-Ellison syndrome, should avoid Betaine HCl as they may experience irritation or reduced healing of ulcers due to the hydrochloric acid in Betaine HCl.

Drug Interactions

Fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs, although this may not be clinically significant. (11) Fenugreek may reduce blood glucose levels and may be additive to hypoglycemic drugs. Monitor blood glucose levels closely. (12)

  1. Hsu, M., Safadi, A.O., & Lui, F. (2022). Physiology, Stomach. In: StatPearls [Internet]. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK535425/
  2. Sarker, S.A., Ahmed, T., & Brüssow, H. (2017). Hunger and microbiology: Is a low gastric acid-induced bacterial overgrowth in the small intestine a contributor to malnutrition in developing countries? Microb Biotechnol, 10(5), 1025-30.
  3. Patricia, J.J., & Dhamoon, A.S. (2022). Physiology, Digestion. In: StatPearls. StatPearls Publishing. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK544242/
  4. Heidelbaugh, J.J. (2013). Proton pump inhibitors and risk of vitamin and mineral deficiency: Evidence and clinical implications. Ther Adv Drug Saf, 4(3), 125-33.
  5. Pizzorno, J.E., & Murray, M.T. (2021). The textbook of natural medicine. 5th ed. Elsevier.
  6. Rafsky, H.A., & Weingarten, M. (1947). A study of the gastric secretory response in the aged. Gastroenterology, 8(3), 348-52.
  7. Davies, D.T., &  James, T.G. (1930). An investigation into the gastric secretion of a hundred normal persons over the age of sixty. QJM, 24(93), 1-14.
  8. Baron, J.H. (1963). Studies of basal and peak acid output with an augmented histamine test. Gut, 4(2), 136-44.
  9. Kelly, G.S. (1997). Hydrochloric acid: Physiological functions and clinical implications. Alt Med Rev, 2(2), 116-27.
  10. Drugs and Lactation Database (LactMed). (2006). Fenugreek. Bethesda (MD): National Library of Medicine (US). Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK501779/
  11. Izzo, A.A., Di Carlo, G., Borrelli, F., et al. (2005). Cardiovascular pharmacotherapy and herbal medicines: The risk of drug interaction. Int J Cardiol, 98(1), 1-14. 
  12. Gong, J., Fang, K., Dong, H., et al. (2016). Effect of fenugreek on hyperglycaemia and hyperlipidemia in diabetes and prediabetes: A meta-analysis. J Ethnopharmacol, 194, 260-8